Even if you take AC requirements from the ecuation by using a power adaptor, I'm pretty sure it would be one nice bottleneck waiting to collapse, expect some extra hate from the windows users.
Since USB3 seems to be problematic at the moment and firewire is kinda rare, we'll have to wait for thunderbolt to evolve or USB3 to become a trusty standard.
If they keep a different port for audio, then it might be possible.
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